Depression ‘may lead to dementia’
About Health –
Accessibility links
- Mobiles
- Skip to content
- Skip to local navigation
- Skip to bbc.co.uk navigation
- Skip to bbc.co.uk search
- Help
- Accessibility Help
- Access keys help
~RS~q~RS~~RS~z~RS~03~RS~)
Depression may double dementia risk, say researchers
Page last updated at 01:09 GMT, Tuesday, 6 July 2010 02:09 UK
- E-mail this to a friend
An estimated 750,000 people in the UK suffer from a form of dementia
Having depression may nearly double the risk of developing dementia later in life, new research suggests.
Experts know that the two conditions often co-exist, but it is not clear if one actually leads to the other.
Now two studies published in the American journal Neurology suggest depression does mean dementia is more likely, although they do not show why.
And the researchers stress that the findings merely reveal a link, not a direct cause.
They say more studies are needed to find out why the two conditions are linked.
They believe brain chemistry and lifestyle factors like diet and the amount of social time a person engages in may play a role.
Dr Jane Saczynski of the University of Massachusetts, who led the first of the two studies, said: "While it's unclear if depression causes dementia, there are a number of ways depression might impact the risk of dementia.
What this study demonstrates is that depression at a younger age is probably a significant risk factor for dementia
Professor Clive Ballard
The Alzheimer’s Society
"Inflammation of brain tissue that occurs when a person is depressed might contribute to dementia. Certain proteins found in the brain that increase with depression may also increase the risk of developing dementia."
Her study, which followed 949 elderly people for 17 years, showed dementia more often followed a bout of depression.
By the end of the study, 164 of the people had developed dementia.
Specifically, 22% of those who had depression went on to develop dementia compared to 17% of those who did not have depression.
The second study, meanwhile, followed 1,239 US people and looked at the number of times a person experienced depression related to their risk of dementia.
It showed that the more times someone experienced depression, the higher their dementia risk was.
Having two or more episodes of depression nearly doubled the risk of dementia.
Rebecca Wood, chief executive of the Alzheimer's Research Trust, said: "Similarities in symptoms between dementia and depression can mean the two are sometimes confused at time of diagnosis, but we don't know if they are biologically linked.
"These latest studies suggest that there may be profound connections between dementia and depression so we must expand the research to find out more."
Professor Clive Ballard of the Alzheimer's Society agreed that more research was now needed to establish why the link exists.
"It is well known depression is common in early stages of dementia. What this study demonstrates is that depression at a younger age is probably a significant risk factor for dementia," he said.
Bookmark with
-
Delicious
-
Digg
-
Facebook
-
reddit
-
StumbleUpon
What are these?
- E-mail this to a friend
Print Sponsor
See also
-
Depression linked to Alzheimer’s
07 April 08Health
-
Q&A: Dementia
03 February 10Health
[an error occurred while processing this directive]
FEATURES, VIEWS, ANALYSIS
-
End of a golden era or stopping a gravy train in its tracks?
-
Can a million people join forces to solve a problem?
-
Clinton’s balancing act between Russia and its neighbours
Skip to top
Products & services
- E-mail news
- Mobiles
- Alerts
- News feeds
- Podcasts
Skip to the top of the page
bbc.co.uk navigation
Site links
- News Sources
- About BBC News
BBC links
- About the BBC
- BBC Help
- Contact Us
- Accessibility Help
- Terms of Use
- Privacy & Cookies
- Advertise With Us
© MMX
The BBC is not responsible for the content of external sites. Read more.
This page is best viewed in an up-to-date web browser with style sheets (CSS) enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience. Please consider upgrading your browser software or enabling style sheets (CSS) if you are able to do so.
